


Q-Lab/Electrophysiology and Behaviour Research Group
Art of Circuits!
“At Q-Lab, our primary research focus is interoceptive memory, the brain’s capacity to encode, store, and retrieve internal bodily signals such as hunger, satiety, heart rate, and visceral feedback. We investigate how these internal states influence cognition, emotion, and metabolic regulation, aiming to uncover their role in both physiological and pathological processes. Building on this central focus, we explore the intricate architecture and dynamic interplay of neural circuits that define brain function and behavior. The structural and functional mapping of these circuits -particularly those involved in interoception- is at the heart of our research. By utilizing cutting-edge techniques such as optogenetics, fiber photometry, and advanced imaging, we aim to unravel the complex mechanisms of neuronal communication and connectivity that underlie interoceptive processes and their influence on behavior and metabolism.”
Research Overview
Research Approach
- Feeding & Metabolism
- Neurophysiology & Behavior
- Neuroendocrinology
- Alzheimer’s Disease & Neurodegeneration
- Circadian Rhythms & Regeneration
- Artificial Intelligence & Bionics
- Neurocancer & Immunology
NeuroHypotesis
By combining the questions of clinical experience with the potential of basic science, we develop hypotheses about how the nervous system works.
Scientific Inovation
We try to transform the basic findings and phenomena emerging during the research process into innovative solutions that will make our daily life easier.
Translational Reseachs
By establishing links between life sciences, engineering, social sciences and arts, we develop the courage to say new words about the future.
News

New Social Activity / Birthday Celebration
The Q-Lab team came together to celebrate the birthday of Büşra Züleyha Doğan, one of our esteemed members. This special occasion was combined with our Neurohypothesis Meeting, creating a unique and lively atmosphere where science and celebration intertwined.
The event provided an excellent opportunity for team bonding while discussing innovative ideas and advancing ongoing research. Warm birthday wishes to Büşra Züleyha Doğan, and congratulations to the team for their collaborative spirit and dedication to scientific excellence.
New Research Presentation / SFN24 Conference
A study on thymic involution, conducted at the intersection of immunology and metabolism as part of Ümmügülsüm Önal‘s(MD) thesis, was presented as a poster at the SFN24 conference. The research focuses on age-related changes in the thymus, exploring the histomorphological and pathophysiological impacts of thymic involution. By mapping blood vessels and neuronal networks in normal histological thymic tissue from young and elderly individuals, the study aims to shed light on the less understood aspects of the aging-related involution process.
Acknowledgments are extended to the mentors who provided guidance throughout the research. Congratulations to all contributing authors on this achievement.


New Social Activity / Lab Picnic
As summer in Istanbul draws to a close, the lab team gathered for a picnic to enjoy the last sunny days and boost our motivation. Surrounded by nature, we took the opportunity to discuss new hypotheses in an open and inspiring environment. This outdoor activity not only fostered creativity but also strengthened our team spirit.
New Award / TÜBİTAK 2214A
We are proud to announce that our PhD student, Aslıhan Atar, has been awarded the prestigious TÜBİTAK 2214-A International PhD Research Fellowship. As part of this fellowship, she will conduct advanced research at the University of Iowa, focusing on AgRP neurons and hypothalamic GABAergic circuits, under the guidance of Dr. Deniz Atasoy. This achievement highlights her dedication and academic excellence. We extend our heartfelt congratulations to Aslıhan Atar and wish her continued success in her research endeavors.


New Graduation / Master Thesis
Our master student Serra Özcan successfully completed her master’s thesis, focusing on the impact of Type 2 Diabetes on brain health. Her research investigated the hippocampus and cerebellum volumes in diabetic patients, exploring the effects of central insulin receptors on brain function. By shedding light on how diabetes affects critical brain regions, this study provides valuable insights into the neurological consequences of the disease. Serra Özcan’s work paves the way for a deeper understanding of the link between metabolic disorders and brain health.