Assist. Prof. Neşe Ayşit
Holds a BSc and an MSc degree in Zoology from Yüzüncü Yıl University. She completed her Master’s thesis in Neuroscience Department, working on Dorsal Root Ganglion cells. Master thesis Investigion Of Roles Of Transcription Fctors Elk-1 and Pea-3 Proteins in Axonal Regeneration and Degeneration.She obtained PhD degree from Istanbul University Neuroscince Departmant , working on ion channel effects of the antibodies on neuronal membrane. She is interested molecular mechanisms after axotomy injury in dorsal root ganglion neurons using advanced microscopic and molecular techniques. Further studies of the crosstalk with neuron and cancer cells,gold nanoparticles and gold nanorods and look at their toxicity, biodistribution, cellular localization and potential therapeutic.She works in SABITA as a researcher since 2013, she is played active role in the establisment of the research center. She is responsible for the cell culture laboratory in the research center.Selected Publications;
The Effects of Surface Functionality and Size of Gold Nanoparticles on Neuronal Toxicity, Apoptosis, ROS Production and Cellular/Suborgan Biodistribution.
Ozcicek, I., Aysit, N., Cakici, C., & Aydeger, A. The Effects of Surface Functionality and Size of Gold Nanoparticles on Neuronal Toxicity, Apoptosis, ROS Production and Cellular/Suborgan Biodistribution. Materials Science and Engineering: C, 128, 112308. (2021)
Bioinspired Scaffold Induced Regeneration of Neural Tissue.
Altun,E., Aydogdu, M. O, Togay,S. O., Sengil A.Z., Ekren N., E Haskoylu M., T Oner E., Aysit N., Ozturk G., Crabbe-Mann, Jubair Ahmed,M., Gunduz O.,Edirisinghe M. Bioinspired Scaffold Induced Regeneration of Neural Tissue. European Polymer Journal 114, 98-108 (2019)
Effects of Ginkgo Biloba Components and Calcium Channel Blockers on Cortical Neuron Excitability in WAG/Rij Rats with Absence Epilepsy: In Vitro Calcium Imaging Study.
Akca M., Bay, S. Baydas G., Aysit N., Ozturk G., Yildirim M. Effects of Ginkgo Biloba Components and Calcium Channel Blockers on Cortical Neuron Excitability in WAG/Rij Rats with Absence Epilepsy: In Vitro Calcium Imaging Study. ACTA PHYSIOLOGICA, 227, 44–44. .(2019).
Effect of Ginkgo Biloba Extract Egb 761 on Intracellular Calcium Level and Excitability in Wag/Rij Rat Cortical Neuron Culture.
Akca M., Yıldırım,M. Baydaş G., Bay S., Aysit N., Gurkan Oztüurk G. Effect of Ginkgo Biloba Extract Egb 761 on Intracellular Calcium Level and Excitability in Wag/Rij Rat Cortical Neuron Culture. Acta Physiologica, 227, 66-66. (2019).
The Neuroprotective Effects of Hypothermia on Bilirubin-Induced Neurotoxicity in Vitro.
Kuter N., Aysit-Altuncu N., Ozturk G., and Ozek E.. "The Neuroprotective Effects of Hypothermia on Bilirubin-Induced Neurotoxicity in Vitro." Neonatology 113, no. 4 (2018): 360-365.(2018)
Effect of LGI1 Antibody-Positive IgG on Hippocampal Neuron Survival: a Preliminary Study.
Ayşit-Altuncu, N., Ulusoy, C., Ozturk G. and Tuzun E. "Effect of LGI1 Antibody-Positive IgG on Hippocampal Neuron Survival: a Preliminary Study." Neuroreport 29, no. 11 932-938. (2018).
CACNA1H Antibodies Associated with Headache with Neurological Deficits and Cerebrospinal Fluid Lymphocytosis (HaNDL).
Kürtüncü M., Kaya, D., Zuliani L., Erdağ E., İçöz S., Uğurel E., Çavuş, F., Ayşit N., Birişik O., Vincent A., Eraksoy M., Vural B., Akman-Demir G., Tüzün E. CACNA1H Antibodies Associated with Headache with Neurological Deficits and Cerebrospinal Fluid Lymphocytosis (HaNDL). Cephalalgia, 33(2), 123-129. (2013)
Two Distinct Types of Dying Back Axonal Degeneration in Vitro.
Öztürk, G., Cengiz, N., Erdoğan, E., Him, A., Oğuz, E. K., Yenidünya, E., & Ayşit, N. Two Distinct Types of Dying Back Axonal Degeneration in Vitro. Neuropathology and applied neurobiology, 39(4), 362-376. (2013).
ETS-Domain Transcription Factor Elk-1 Mediates Neuronal Survival: SMN as a Potential Target.
Demir, O., Aysit, N., Onder, Z., Turkel, N., Ozturk, G., Sharrocks, A. D., & Kurnaz, I. A. . ETS-Domain Transcription Factor Elk-1 Mediates Neuronal Survival: SMN as a Potential Target. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1812(6), 652-662. (2011).