Assoc. Prof. Seda Karabulut
[email protected]Assoc. Prof. Dr. Seda Karabulut completed her PhD in Molecular Biology and Genetics at Gebze Institute of Technology. She has 20 years of clinical experience in assisted reproductive technologies, having worked as a clinical embryologist and laboratory director at leading IVF centers in Türkiye, where she established and managed IVF laboratories. She also gained international research experience at CCRM Fertility in Denver, USA.
She is currently a faculty member and Head of the Department of Histology and Embryology at the International School of Medicine, Istanbul Medipol University.
Dr. Karabulut has authored numerous national and international publications, conference presentations, and book chapters, and has participated in and led various national and international research projects. She is also an inventor with multiple national and international patents in assisted reproductive technologies and sperm selection.
Her research focuses on infertility, reproductive biology and medicine, gamete biology, sperm selection techniques, and reproductive biotechnology, with an emphasis on translating scientific research into innovative applications in assisted reproductive medicine.
Selected Publications;
A Histopathological Evaluation of Ovarian Hyperstimulation Syndrome on Reproductive and Vital Organs and the Role of the VEGF-PKA Pathway in a Mouse Model.
Karabulut, S., Korkmaz, O., Erdem Altun, C. ve Keskin, İ. (2021). A histopathological evaluation of ovarian hyperstimulation syndrome on reproductive and vital organs and the role of the VEGF-PKA pathway in a mouse model. Cells Tissues Organs, 210(3), 218-237.
Effects of Gallic Acid on Endometrial Cancer Cells in Two and Three Dimensional Cell Culture Models.
Bülbül, M. V., Karabulut, S., Kalender, M. ve Keskin, İ. (2021). Effects of Gallic Acid on Endometrial Cancer Cells in Two and Three Dimensional Cell Culture Models. Asian Pacific Journal of Cancer Prevention, 22(6), 1745-1751.
Chronic Unpredictable Stress Disturbs the Blood-Testis Barrier Affecting Sperm Parameters in Mice.
Kolbaşı, B., Bülbül, M. V., Karabulut, S., Erdem Altun, C., Çakıcı, Ç., Ülfer, G. ... Keskin, İ. (2021). Chronic Unpredictable Stress Disturbs the Blood-Testis Barrier Affecting Sperm Parameters in Mice. Reproductive BioMedicine Online, 42(5), 983-995.
Seminal Oxidation–Reduction Potential as a Possible Indicator of Impaired Sperm Parameters in Turkish Population.
Karabulut, S., Korkmaz, O., Yılmaz, E. ve Keskin, İ. (2021). Seminal Oxidation-Reduction Potential as a Possible Indicator of Impaired Sperm Parameters in Turkish Population. Andrologia, 53(2). https://dx.doi.org/10.1111/and.13956
Factors Related to Follicular Oxidative Stress in Intracytoplasmic Sperm Injection Cycles and its Effects on Granulosa Cells.
Karabulut, S., Korkmaz, O., Kutlu, P. ve Keskin, İ. (2021). Factors Related to Follicular Oxidative Stress in Intracytoplasmic Sperm Injection Cycles and its Effects on Granulosa Cells. Zygote, 29(1), 59-65. https://dx.doi.org/10.1017/S0967199420000520
Effects o Follicular Fluid Oxidative Status on Human Mural Granulosa Cells, Oocyte Competency and ICSI Parameters.
Karabulut, S., Korkmaz, O., Kutlu, P., Eren Gözel, H. ve Keskin, İ. (2020). Effects o Follicular Fluid Oxidative Status on Human Mural Granulosa Cells, Oocyte Competency and ICSI Parameters. European Journal of Obstetrics & Gynecology and Reproductive Biology, 252, 127-136. https://dx.doi.org/10.1016/j.ejogrb.2020.06.021
Does a Microfluidic Chip for Sperm Sorting Have a Positive add-on Effect on Laboratory and Clinical Outcomes of Intracytoplasmic Sperm Injection Cycles? A Sibling Oocyte Study.
Yalçınkaya Kalyan, E., Can Çelik, S., Okan, Ö., Akdeniz, G., Karabulut, S. ve Çalışkan, E. (2019). Does a Microfluidic Chip for Sperm Sorting Have a Positive add-on Effect on Laboratory and Clinical Outcomes of Intracytoplasmic Sperm Injection Cycles? A Sibling Oocyte Study. Andrologia, 51(10). https://doi.org/10.1111/and.13403
Intracytoplasmic Morphologically Selected Sperm Injection, but for Whom?
Karabulut, S., Aksünger, Ö., Korkmaz, O., Eren Gozel, H. ve Keskin, İ. (2019). Intracytoplasmic Morphologically Selected Sperm Injection, but for Whom? Zygote, 27(5), 299-304. https://doi.org/10.1017/S0967199419000297
No Benefit of Reduced Oxygen Level for the Culture of Human Embryos In Vitro.
No Benefit of Reduced Oxygen Level for the Culture of Human Embryos In Vitro Annals of Infertility & Reproductive Endocrinology Seda Karabulut, Pelin Kutlu Oya Korkmaz and İlknur Keskin. 2019 | Volume 2 | Issue 1 | Article 1013
Effects of Early Embryo Cleavage on Embryo Quality and Pregnancy Outcome.
Effects of Early Embryo Cleavage on Embryo Quality and Pregnancy Outcome. Karabulut S, Yilmaz E, Korkmaz O, Keskin I. Ann Infert Rep Endocrin. 2018; 1(2): 1010.
Effects of Human Sperm Cryopreservation on Apoptotic Markers in Normozoospermic and Non-Normozoospermic Patients.
Effects of human sperm cryopreservation on apoptotic markers in normozoospermic and non-normozoospermic patients. Karabulut S, Demiroğlu-Zergeroğlu A, Yılmaz E, Kutlu P, Keskin İ. Zygote. 2018 Sep 17:1-6. doi: 10.1017/S0967199418000254.
Artificial Oocyte Activation with Calcium Lonophore for Frozen Sperm Cycles.
Artificial Oocyte Activation with Calcium Lonophore for Frozen Sperm Cycles. Karabulut S. Aksünger Ö. Ata C. Sağıroglu Y. Keskin İ. Syst Biol Reprod Med. 2018 Oct;64(5):381-388. doi: 10.1080/19396368.2018.1452311. Epub 2018 Apr 5.
Relationship Between Semen Parameters in Samples Obtained from Sub-Fertile Patients.
Relationship Between Semen Parameters in Samples Obtained from Sub-Fertile Patients Andrology- (Los Angel) 2017 Open Access Karabulut et al., Andrology (Los Angel) 2017, 6:2 DOI: 10.4172/2167-0250.1000180. Seda Karabulut, Ilknur Keskin,Yusuf Sagıroglu.
P53 and Mitogen-Activated Protein Kinase Pathway Protein Profiles in Fresh and Frozen Spermatozoa.
P53 and Mitogen-Activated Protein Kinase Pathway Protein Profiles in Fresh and Frozen Spermatozoa. S. Karabulut, A. Demiroglu-Zergeroglu, E. Yılmaz, F. Sagır & N. Delikara. Andrologia 2014 Dec;46(10):1113-7.
Increased Sperm DNA Damage in Experimental Rat Varicocele Model and Beneficial Effect of Varicocelectomy.
Increased Sperm DNA Damage in Experimental Rat Varicocele Model and Beneficial Effect of Varicocelectomy. Metin İshak Öztürk, MD, Orhan Koca, MD, Oğuz Keleş, MD, Seda Yılmaz, MSc, Muhammet Ihsan Karaman, Prof. International Journal of Fertility and Sterility (IJFS); Vol:6, No:2, Jul-Sep 2012.
Ekim 2, 2026
What if sperm selection in IVF could look beyond what can be seen under the microscope? A patented technology developed by Assoc. Prof. Seda Karabulut at […]
Mart 28, 2023
We present you the new episode of our podcast series on artificial embryos, one of Dr. Seda Karabulut‘s research topics. In this podcast, we talked about […]