2010-2013 Research Assistant : New York University Department of Neurology , New York , USA
2007-2009 Research Assistant : Karolinska Institute Cell and Gene Therapy Group , Stockholm , Sweden,
2004-2009 Bachelor of Science : B.S. Bilkent University Department of Molecular Biology and Genetics , Ankara , Turkey
2007-2009 Research Assistant : Karolinska Institute Cell and Gene Therapy Group , Stockholm , Sweden,
2004-2009 Bachelor of Science : B.S. Bilkent University Department of Molecular Biology and Genetics , Ankara , Turkey
Selected Publications;
Lithium promotes long-term neurological recovery after spinal cord injury in mice by enhancing neuronal survival, gray and white matter remodeling, and long-distance axonal regeneration
Balçıkanlı Z, Culha I, Dilsiz P, Aydin MS, Ates N, Beker MC, Baltaci SB, Koc HI, Yigitbasi A, Gündogar M, Doeppner TR, Hermann DM, Kilic E. Lithium promotes long-term neurological recovery after spinal cord injury in mice by enhancing neuronal survival, gray and white matter remodeling, and long-distance axonal regeneration. Front Cell Neurosci. 2022 Nov 11;16:1012523. doi: 10.3389/fncel.2022.1012523. PMID: 36439202; PMCID: PMC9693752.
Protein and Gene Delivery Systems for Neurodegenerative Disorders: Where Do We Stand Today?
Siafaka PI, Okur ME, Erim PD, Çağlar EŞ, Özgenç E, Gündoğdu E, Köprülü REP, Karantas ID, Üstündağ Okur N. Protein and Gene Delivery Systems for Neurodegenerative Disorders: Where Do We Stand Today? Pharmaceutics. 2022 Nov 10;14(11):2425. doi: 10.3390/pharmaceutics14112425. PMID: 36365243; PMCID: PMC9698227.
Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
Ates N, Caglayan A, Balcikanli Z, Sertel E, Beker MC, Dilsiz P, Caglayan AB, Celik S, Dasdelen MF, Caglayan B, Yigitbasi T, Ozbek H, Doeppner TR, Hermann DM, Kilic E. Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice. Exp Neurol. 2022 May;351:113996. doi: 10.1016/j.expneurol.2022.113996. Epub 2022 Feb 2. PMID: 35122865.
Detecting and targeting neurodegenerative disorders using electrospun nanofibrous matrices: current status and applications
Siafaka PI, Özcan Bülbül E, Dilsiz P, Karantas ID, Okur ME, Üstündağ Okur N. Detecting and targeting neurodegenerative disorders using electrospun nanofibrous matrices: current status and applications. J Drug Target. 2021 Jun;29(5):476-490. doi: 10.1080/1061186X.2020.1859516. Epub 2021 Jan 5. PMID: 33269637.
MCH Neuron Activity Is Sufficient for Reward and Reinforces Feeding
Dilsiz P, Aklan I, Sayar Atasoy N, Yavuz Y, Filiz G, Koksalar F, Ates T, Oncul M, Coban I, Ates Oz E, Cebecioglu U, Alp MI, Yilmaz B, Atasoy D. MCH Neuron Activity Is Sufficient for Reward and Reinforces Feeding. Neuroendocrinology. 2020;110(3-4):258-270. doi: 10.1159/000501234. Epub 2019 Jun 3. PMID: 31154452.
NTS Catecholamine Neurons Mediate Hypoglycemic Hunger via Medial Hypothalamic Feeding Pathways
Aklan I, Sayar Atasoy N, Yavuz Y, Ates T, Coban I, Koksalar F, Filiz G, Topcu IC, Oncul M, Dilsiz P, Cebecioglu U, Alp MI, Yilmaz B, Davis DR, Hajdukiewicz K, Saito K, Konopka W, Cui H, Atasoy D. NTS Catecholamine Neurons Mediate Hypoglycemic Hunger via Medial Hypothalamic Feeding Pathways. Cell Metab. 2020 Feb 4;31(2):313-326.e5. doi: 10.1016/j.cmet.2019.11.016. Epub 2019 Dec 12. PMID: 31839488; PMCID: PMC9017597.
Inactivation of Magel2 Suppresses Oxytocin Neurons Through Synaptic Excitation-Inhibition Imbalance
Ates T, Oncul M, Dilsiz P, Topcu IC, Civas CC, Alp MI, Aklan I, Ates Oz E, Yavuz Y, Yilmaz B, Sayar Atasoy N, Atasoy D. Inactivation of Magel2 suppresses oxytocin neurons through synaptic excitation-inhibition imbalance. Neurobiol Dis. 2019 Jan;121:58-64. doi: 10.1016/j.nbd.2018.09.017. Epub 2018 Sep 19. PMID: 30240706.
Impaired melanocortin pathway function in Prader-Willi syndrome gene-Magel2 deficient mice
Oncul M, Dilsiz P, Ates Oz E, Ates T, Aklan I, Celik E, Sayar Atasoy N, Atasoy D. Impaired melanocortin pathway function in Prader-Willi syndrome gene-Magel2 deficient mice. Hum Mol Genet. 2018 Sep 15;27(18):3129-3136. doi: 10.1093/hmg/ddy216. PMID: 29878108.
Neuronal Tsc1/2 Complex Controls Autophagy Through AMPK and mTORC1-dependent Regulation of Ulk1.
Di Nardo A., Wertz MH., Kwiatkowski E., Tsai PT., Leech JD., Greene-Colozzi E., Goto J.,
Dilsiz P., Talos DM., Clish CB., Kwiatkowski DJ., Sahin M., Neuronal Tsc1/2 complex controls
autophagy through AMPK and mTORC1-dependent regulation of Ulk1. Hum Mol Genet. 2014 Jul 15;23(14):3865-74
Developmental Abnormalities in Human TSC Brain: A Comparative Analysis of Tuberal and Perituberal Cortex.
Ruppe V., Dilsiz P., Reiss CS., Carlson C., Devinsky O., Zagzag D., Weiner HL., Talos DM.,
Developmental Abnormalities in Human TSC Brain: A Comparative Analysis of Tuberal and Perituberal
Cortex. Epilepsia 2014 Apr;55(4):539-50