Assist. Prof. Muzaffer Arıkan

Muzaffer Arıkan's academic background includes a BSc in Molecular Biology and Genetics from Istanbul Technical University, a MSc in Genetics from the Aziz Sancar Institute for Experimental Medical Research and a PhD in Molecular Biology and Genetics from Istanbul University. His PhD work focused on the microbial composition of fermented foods using both amplicon sequencing and shotgun metagenomics. During the bioinformatics part of his project, he worked in EMBL-EBI Metagenomics team as a visiting researcher for one year. In his postdoctoral studies, he investigated the role of human microbiome in Parkinson's disease applying a combination of NGS based 16S rRNA gene amplicon sequencing, metagenomics, metaproteomics and imaging analysis.

Dr. Arıkan is currently holding a faculty position in the Department of Medical Biology in the School of Medicine. His research focuses on understanding structure and function of microbial communities through multi-omics analyses.

Selected Publications;

Axillary Microbiota is Associated with Cognitive Impairment in Parkinson's Disease Patients

Axillary Microbiota is Associated with Cognitive Impairment in Parkinson's Disease Patients. Arıkan M, Yildiz Z, Kahraman Demir T, Yilmaz NH, Sen A, Hanoglu L, Yildirim S. MSpectrum. 2022. 10(1), e02358-21.

Stratification of the Gut Microbiota Composition Landscape Across the Alzheimer’s Disease Continuum in a Turkish Cohort

Stratification of the Gut Microbiota Composition Landscape Across the Alzheimer’s Disease Continuum in a Turkish Cohort. Yıldırım S, Nalbantoğlu ÖU, Bayraktar A, Ercan FB, Gündoğdu A, Velioğlu HA, Göl MF, Ekinci Soylu A, Koç F, Aslan Gürpınar E, Sogukkanlı Kadak K, Arıkan M, Mardinoğlu A, Koçak M, Köseoğlu E, Hanoğlu L. MSystems. 2022. 7(1), e00004-22.

Microbial Composition of Kombucha Determined Using Amplicon Sequencing and Shotgun Metagenomics

Microbial Composition of Kombucha Determined Using Amplicon Sequencing and Shotgun Metagenomics. Arıkan M, Mitchell A, Finn RD, Gurel F. Journal of Food Science. 2020, 85(2):455-464.

Next Generation Sequencing: Advantages, Disadvantages and Future

Next Generation Sequencing: Advantages, Disadvantages and Future. Arı Ş & Arıkan M. In Plant Omics: Trends and Applications Hakeem K et al. (eds.) pp. 109-135, 2016, Springer International Publishing, Switzerland.

Water as Source of Francisella Tularensis Infection in Humans, Turkey

Water as Source of Francisella Tularensis Infection in Humans, Turkey. Kilic S, Birdsell DN, Karagöz A, Çelebi B, Bakkaloglu Z, Arikan M, Sahl JW, Mitchell C, Rivera A, Maltinsky S, Keim P, Üstek D, Durmaz R, Wagner DM. Emerging Infectious Diseases. 2015, 21(12):2213.

Mitochondrial Mutations in Patients with Congenital Heart Defects by Next Generation Sequencing Technology

Mitochondrial Mutations in Patients with Congenital Heart Defects by Next Generation Sequencing Technology. Abaci N, Arıkan M, Tansel T, Sahin N, Cakiris A, Pacal F, Sırma Ekmekci S, Gök E, Üstek D. Cardiol Young. 2015, 25(4):705-711.

Mitochondrial DNA Profiling via Genomic Analysis in Mesial Temporal Lobe Epilepsy Patients with Hippocampal Sclerosis

Mitochondrial DNA Profiling via Genomic Analysis in Mesial Temporal Lobe Epilepsy Patients with Hippocampal Sclerosis. Gurses C, Azakli H, Alptekin A, Cakiris A, Abaci N, Arikan M, Kursun O, Gokyigit A, Ustek D. Gene. 2014, 538(2):323-327.

The Role of INNO-LiPA HBV DR and Ultra-Deep Pyrosequencing in Detecting the Resistance Mutations to Nucleoside/Nucleotide Analogues in Viral Samples Isolated from Chronic Hepatitis B Patients

The Role of INNO-LiPA HBV DR and Ultra-Deep Pyrosequencing in Detecting the Resistance Mutations to Nucleoside/Nucleotide Analogues in Viral Samples Isolated from Chronic Hepatitis B Patients. Mese S, Arikan M, Cakiris A, Abaci N, Gumus E, Kursun O, Onel D, Ustek D, Kaymakoglu S, Badur S, Yenen OS, Bozkaya E. J Gen Virol. 2013, 94(12):2729-2738.

Whole Mitochondrial Genome Analysis of a Family with NARP/MILS Caused by m.8993T>C Mutation in the MT-ATP6 Gene

Whole Mitochondrial Genome Analysis of a Family with NARP/MILS Caused by m.8993T>C Mutation in the MT-ATP6 Gene. Kara B, Arıkan M, Maraş H, Abacı N, Cakıris A, Ustek D. Mol Genet Metab. 2012, 107(3):389-393.

A Genome-Wide Analysis of Lentivector Integration Sites Using Targeted Sequence Capture and Next Generation Sequencing Technology

A Genome-Wide Analysis of Lentivector Integration Sites Using Targeted Sequence Capture and Next Generation Sequencing Technology. Ustek D, Sirma S, Gumus E, Arikan M, Cakiris A, Abaci N, Mathew J, Emrence Z, Azakli H, Cosan F, Çakar A, Parlak M, Kurşun O. Infect Genet Evol. 2012, 12(7):1349-1354.

Draft Genome Sequence of Halomonas Smyrnensis AAD6T

Draft Genome Sequence of Halomonas Smyrnensis AAD6T. Sogutcu E, Emrence Z, Arikan M, Cakiris A, Abaci N, Oner ET, Ustek D, Arga KY. J Bacteriol. 2012, 194(20):5690-5691.