Nilay Ateş Özsoy
Nilay Ateş Özsoy graduated from Istanbul Medipol University Faculty of Pharmacy in 2017. Subsequently, she received her Medical Pharmacology Ph.D. degree from Istanbul Medipol University in 2022. Her main research area is about investigating the possible pharmacological treatment background of neurodegenerative diseases. Specifically, in her Ph.D. study, she was interested in the cellular and molecular mechanisms of cerebral ischemia. Depending on this topic, she examined the effects of lithium on the regulatory mechanisms of neurogenesis after cerebral ischemia. As a member of Prof. Dr. Ertuğrul Kılıç's team, by combining the Physiology Laboratory experience with Medical Pharmacology degree, she has improved some research skills of applying animal model of middle cerebral artery occlusion in mice, performing electrophysiological measurements, cannulation methods of tail, femoral and carotid artery, intracranial injection, and cardiac perfusion-fixation in mice. Moreover, she also has experience in Western Blot protein analysis, molecular staining techniques of immunohistochemistry and immunofluorescence. Dr. Ateş is currently pursuing her career by taking coordinator roles in some projects about performing new therapeutical approaches for neurodegenerative diseases and holding a faculty position in the Medical Pharmacology department in the Faculty of Medicine.Selected Publications;
Neuroprotective effect of lithium in cold-induced traumatic brain injury in mice
CIFTCI, Elvan, et al. Neuroprotective effect of lithium in cold-induced traumatic brain injury in mice. Behavioural Brain Research, 2020, 392: 112719.
Short-term diet restriction but not alternate day fasting prevents cisplatin-induced nephrotoxicity in mice
GUNEBAKAN, Evrin, et al. Short-term diet restriction but not alternate day fasting prevents cisplatin-induced nephrotoxicity in mice. Biomedicines, 2020, 8.2: 23.
The Unconventional Growth Factors Cerebral Dopamine Neurotrophic Factor and Mesencephalic Astrocyte–Derived Neurotrophic Factor Promote Post-ischemic Neurological Recovery, Perilesional Brain Remodeling, and Lesion-Remote Axonal Plasticity
CAGLAYAN, Ahmet Burak, et al. The Unconventional Growth Factors Cerebral Dopamine Neurotrophic Factor and Mesencephalic Astrocyte–Derived Neurotrophic Factor Promote Post-ischemic Neurological Recovery, Perilesional Brain Remodeling, and Lesion-Remote Axonal Plasticity. Translational stroke research, 2022, 1-15.
Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
ATES, Nilay, et al. Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice. Experimental Neurology, 2022, 351: 113996.
Phosphodiesterase 10A is a critical target for neuroprotection in a mouse model of ischemic stroke
BEKER, Mustafa C., et al. Phosphodiesterase 10A is a critical target for neuroprotection in a mouse model of ischemic stroke. Molecular Neurobiology, 2022, 59.1: 574-589.