SABITALKS / Drosophila melanogaster as a Model Organism for Research of Human Disease
Dr. Joern Steinert from University of Nottingham is going to be at SABITALKS on July 8, 2025 at 14:00. The event will take place in person.
Location: Istanbul Medipol University North Campus / C Block, 1st Floor, Senate Room
https://goo.gl/maps/JDDjygVtFLWiPiMJA
*Participants from outside SABITA must fill in the participation form.
Drosophila melanogaster as a Model Organism for Research of Human Disease
Cellular functions involving redox signalling are conserved across many species. This talk will provide and overview how Drosophila can be used as a model system to study functional effects of redox signalling utilising the neuromuscular junction synapse and behavioural readouts. These studies will allow models of human disease to be investigated using this relative simple organism given the fact that about 65% of human disease-causing genes have a functional homolog in Drosophila.
Joern Steinert
University of Nottingham
Joern Steinert studied at the Humboldt University Berlin and graduated in 1996 with the Diplom in Biophysics. Following his PhD in Vascular Biology at King’s College London (1997-2001), he took up postdoctoral positions in Tuebingen (2002) and Heidelberg (2004) to study physiological mechanisms of neurotransmission using mammalian and Drosophila model systems. He became Program Leader at the Toxicology Unit in 2013 before starting an Assistant Professor position at the University of Nottingham in 2020. His research focuses on the regulation of neuronal excitability under activity-dependent mechanisms involving nitric oxide signalling and how regulation of the redox homeostasis in neurodegeneration associated with neuroinflammation impacts on neuronal function.
Dr Steinert acts as an Associate Editor for Cell Death Discovery and Review and Associate Editor for Frontiers in Molecular Neuroscience and Frontiers in Synaptic Neuroscience, in addition to serving as a Guest Editor for several journals including Free Radical Biology and Medicine, The Journal of Physiology and Cell Death Disease.