Prof. Dr. Yasemin Yüksel Durmaz
[email protected]Yasemin Yuksel Durmaz graduated from Yildiz Technical University, Department of Chemistry in 2003. She then received her MSc and PhD degree in Istanbul Technical University, Polymer Science and Technology. Following 4 years, she worked as postdoctoral research fellow in Cellular Engineering and Nano-therapeutics Research Laboratory, Department of Biomedical Engineering, University of Michigan. In 2015, she joined in Istanbul Medipol University, School of Engineering and Natural Sciences, Department of Biomedical Engineering and has been directing a research laboratory namely Innovative Polymer Nanotherapeutics Research Laboratory (IPONT). Current research interests are developing new “smart” materials for cellular drug/gene delivery, polymer nanotherapeutics and theranostics.
Selected Publicaitons;
PEGylated reduced graphene oxide as nanoplatform for targeted gene and drug delivery
Erhan Demirel, Yasemin Yuksel Durmaz. PEGylated reduced graphene oxide as nanoplatform for targeted gene and drug delivery. European Polymer Journal. Volume 186. 2023. 111841. ISSN 00 4-3057. https://doi.org/10.1016/j.eurpolymj.2023.111841.
A new strategy for direct solution electrospinning of phosphorylated poly(vinyl chloride)/polyethyleneimine blend in alcohol media
Cagatay Altinkok, Gokhan Sagdic, Ozgun Daglar, Merve Ercan Ayra, Yasemin Yuksel Durmaz, Hakan Durmaz, Gokhan Acik. A new strategy for direct solution electrospinning of phosphorylated poly(vinyl chloride)/polyethyleneimine blend in alcohol media. European Polymer Journal. Volume 183. 2023. 111750. ISSN 0014-3057. https://doi.org/10.1016/j.eurpolymj.2022.111750.
Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy
Toydemir C, Hall S, Demirel E, Elmaci DN, Gol D, Vlaisavljevich E, Yuksel Durmaz Y. Bioconjugated β-Cyclodextrin-Perfluorohexane Nanocone Clusters as Functional Nanoparticles for Nanoparticle-Mediated Histotripsy. Biomacromolecules. 2022 Dec 12;23(12):5297-5311. doi: 10.1021/acs.biomac.2c01110. Epub 2022 Nov 23. PMID: 36418020.
Experimental and Computational Investigation of Clustering Behavior of Cyclodextrin-Perfluorocarbon Inclusion Complexes as Effective Histotripsy Agents
Kaymaz B, Mustafa W, Hall S, Vlaisavljevich E, Sensoy O, Yuksel Durmaz Y. Experimental and Computational Investigation of Clustering Behavior of Cyclodextrin-Perfluorocarbon Inclusion Complexes as Effective Histotripsy Agents. Mol Pharm. 2022 Aug 1;19(8):2907-2921. doi: 10.1021/acs.molpharmaceut.2c00268. Epub 2022 Jul 15. PMID: 35839291.
Formulation of Acid-Sensitive Micelles for Delivery of Cabazitaxel Into Prostate Cancer Cells
Formulation of Acid-Sensitive Micelles for Delivery of Cabazitaxel Into Prostate Cancer Cells, Aydin, I. Youssef, Y. Y. Durmaz, G. Tiruchinapally, M. E. H. El-Sayed, Molecular Pharmaceutics, 2016, 13(4), 1413-1429.
The Effects of Droplet Composition on Nanodroplet-Mediated Histotripsy
The Effects of Droplet Composition on Nanodroplet-Mediated Histotripsy, E. Vlaisavljevich, O. Aydin, Y. Durmaz, K-W. Lin, B. Fowlkes, M. E. H. ElSayed, Z. Xu, Ultrasound in Medicine and Biology, 2016, 42 (4), 931-946.
The Role of Positive and Negative Pressure on Cavitation Nucleation in Nanodroplet-Mediated Histotripsy
The Role of Positive and Negative Pressure on Cavitation Nucleation in Nanodroplet-Mediated Histotripsy, E. Vlaisavljevich, O. Aydin, K-W. Lin, Y. Durmaz, B. Fowlkes, M. E. H. ElSayed, Z. Xu, Physics in Medicine and Biology, 2016, 61, 663-668.
“Smart” Nanoparticles Enhance the Cytoplasmic Delivery of Anti-RhoC silencing RNA and Inhibit the Migration and Invasion of Aggressive Breast Cancer Cells
“Smart” Nanoparticles Enhance the Cytoplasmic Delivery of Anti-RhoC silencing RNA and Inhibit the Migration and Invasion of Aggressive Breast Cancer Cells, N. Kaushal, Y. Durmaz, L. W. Bao, S. D. Merajver, M. E. H. ElSayed, Molecular Pharmaceutics 2015, 12(7), 2406-2417.
The Effects of Ultrasound Frequency on Nanodroplet-Mediated Histotripsy
The Effects of Ultrasound Frequency on Nanodroplet-Mediated Histotripsy, E. Vlaisavljevich, O. Aydin, K.W. Lin, Y. Durmaz, B. Fowlkes, M.E.H. ElSayed, Z. Xu, Ultrasound in Medicine and Biology, 2015, 41(8), 2135-2147.
Development of Nanodroplets for Histotripsy-Mediated Cell Ablation
Development of Nanodroplets for Histotripsy-Mediated Cell Ablation, Y. Durmaz, E. Vlaisavljevich, Z. Xu, M. E. H ElSayed, Molecular Pharmaceutics, 2014, 11(10), 3685-3695.
Nanodroplet-Mediated Histotripsy for Image-guided Targeted Ultrasound Cell Ablation
Nanodroplet-Mediated Histotripsy for Image-guided Targeted Ultrasound Cell Ablation, Vlaisavljevich, Y. Y. Durmaz, A. Maxwell, M. E. H. ElSayed, Z. Xu, Theranostics, 2013, 3(11), 802-815.
Synergistic Combination of Small Molecule Inhibitor and RNA interference Against Anti-apoptotic Bcl-2 Protein in Head and Neck Cancer Cells
Synergistic Combination of Small Molecule Inhibitor and RNA interference Against Anti-apoptotic Bcl-2 Protein in Head and Neck Cancer Cells, Y-L. Lin, Y. Durmaz, J. E. Nör, M. E. H. ElSayed, Molecular Pharmaceutics, 2013, 10, 2730-2738.
Development of Degradable, pH-Sensitive Star Vectors for Enhancing the Cytoplasmic Delivery of Nucleic Acids
Development of Degradable, pH-Sensitive Star Vectors for Enhancing the Cytoplasmic Delivery of Nucleic Acids, Y. Durmaz, Y-L. Lin, M. E. H. ElSayed, Advanced Functional Materials, 2013, 23(31), 3885-3895.
Targeting Hepatic Cancer Cells with PEGylated Dendrimers Displaying N-Acetylgalactosamine and SP94 Peptide Ligands
Targeting Hepatic Cancer Cells with PEGylated Dendrimers Displaying N-Acetylgalactosamine and SP94 Peptide Ligands, H. Medina, G. Tiruchinapally, M. V. Chevliakov,
Y. Y. Durmaz, R. N. Stender, W. D. Ensminger, D. S. Shewach, M. E. H. ElSayed, Advanced Healthcare Materials, 2013, 2(10), 1337-1350.
Enzyme-Activated Nanoconjugates for Tunable Release of Doxorubicin in Hepatic Cancer Cells
Enzyme-Activated Nanoconjugates for Tunable Release of Doxorubicin in Hepatic Cancer Cells, S. H. Medina, M. V. Chevliakov, G. Tiruchinapally, Y. Durmaz, S. P. Kuruvilla, M. E.H. ElSayed, Biometerials, 2013, 36, 4655-4666.
A Novel Poly(p-phenylene) Containing Alternating Poly(perfluorooctylethyl acrylate-co-methyl methacrylate) and Polystyrene Grafts by Combination of Atom Transfer Radical Polymerization and Suzuki Coupling Processes
A Novel Poly(p-phenylene) Containing Alternating Poly(perfluorooctylethyl acrylate-co-methyl methacrylate) and Polystyrene Grafts by Combination of Atom Transfer Radical Polymerization and Suzuki Coupling Processes, Y. Durmaz, E. L. Sahkulubey, Y. Yagci, E. Martinelli, G. Galli, Journal of Polymer Science Part A: Polymer Chemistry 2012, 50(23), 4911-4919.
New Photoinitiating Systems for Cationic Polymerization Acting at Near UV and Visible Range
New Photoinitiating Systems for Cationic Polymerization Acting at Near UV and Visible Range, Aydogan, Y. Y. Durmaz, M. U. Kahveci, M. Uygun, M. A. Tasdelen, Y. Yagci, Macromolar Symposia 2011, 308, 25-34.
Film Formation of Poly(methyl metacrylate) Latex with Pyrene Functional Poly(divinylbenzene) Microspheres Prepared by Click Chemistry
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Mauris eu maFilm Formation of Poly(methyl metacrylate) Latex with Pyrene Functional Poly(divinylbenzene) Microspheres Prepared by Click Chemistry, Ugur, O. Yargi, Y. Y. Durmaz, B. Karagoz, N. Bicak, Y. Yagci, O. Pekcan, Polymer Composites, 2011, 32(6), 869-881.ssa orci.
Modification of Poly(divinylbenzene) Microspheres by Hydrobromination-Click Chemistry Protocol and Their Protein Adsorption Properties
Modification of Poly(divinylbenzene) Microspheres by Hydrobromination-Click Chemistry Protocol and Their Protein Adsorption Properties, Y. Durmaz, B. Karagoz, N. Bicak, D. Odaci, E. Yalcinkaya, S. Timur, Y. Yagci, Macromolecular Bioscience, 2011, 11, 141-150.
Ekim 26, 2022
2022 Nobel Prize Chemistry and Physiology or Medicine The 2022 Nobel Prize in Chemistry and Physiology or Medicine has been announced. In this podcast, Yasemin Yüksel […]