Assist. Prof. A. Arzu Şakul
[email protected]She completed her bachelor’s degree at Ondokuz Mayıs University School of Medicine and has fulfilled her obligatory service as a medical doctor. She has worked in Artvin/ Arhavi State Hospital, Manisa/ Salihli Mother and Child Health Center (AÇS-AP) and Ankara/ Çankaya 3rd AÇS-AP Training Center, respectively. During that time, she worked in family planning, immunization and as a master trainer in various adult education areas. She started her PhD in Medical Pharmacology at Hacettepe University, School of Medicine, Department of Medical Pharmacology and completed it at Gazi University, School of Medicine, Department of Medical Pharmacology. She started her duty in the Refik Saydam Sanitation Chairmanship Center, Poison Research Directorate, Poison Counseling Center. Then, she had training and provided training in toxicology, clinical toxicology) nationally and internationally. She served as a member of the science board and consultancy on drugs and substance addiction at TUBIM (Turkey Drugs and Drug Addiction Monitoring Center) and TADOC (Turkey International Academy for Combating Drugs and Organized Crimes). She was appointed as a faculty member at Istanbul Medipol University, School of Medicine, Department of Medical Pharmacology while coordinating the National Poison Center (UZEM) of the General Directorate of Emergency Health Services of the Ministry of Health in 2014. Her research interest is focused on oxidative stress, ageing and regeneration, anti-ageing, oxidative stress-based diabetes mellitus and drug development in neurodegeneration models, psychopharmacology, and clinical toxicology. She continues to serve as the general coordinator of GETAT training at the university. She completed her training on personal GETAT applications and expanded her pharmacological research studies in phytotherapy and aromatherapy. She continues her research at Istanbul Medipol University Regenerative and Restorative Medicine Research Center and Cancer Research Center.
Selected Publications;
In Vivo Wound-Healing and in Vitro Antibacterial and Antioxidant Properties of Carduus Adpressus Extract
A. A. Şakul, Ş. Ayla, M. E. Okur, A. E. Karadağ, B. Daylan, E. Güzel, E. M. Özdemir & M. Y. Günal. In vivo wound-healing and in vitro antibacterial and antioxidant properties of Carduus adpressus extract. Journal of Research in Pharmacy (2023) Cilt : 27 Sayı : 2 Sayfa : 665-676
Wound Healing Activity of Arum Maculatum
A. A. Şakul, M. E. Okur, Ş. Ayla, B. Daylan, A. E. Karadağ, Ş. Batur, E. M. Özdemir, E. Altınalan & M. Y. Günal. Wound Healing Activity of Arum Maculatum. Medeni Med J. (2023)
Evaluation of Antidiabetic Activities of Scorzonera Species on Alloxan Induced Diabetic Mice
A. A. Şakul, E. Kurtul, H. Özbek, N. İ. Kırmızı, B. C. Bahtiyar, H. G. Saltan İşcan & Ö. Bahadır Acıkara. Evaluation of Antidiabetic Activities of Scorzonera Species on Alloxan Induced Diabetic Mice. Clin Exp Health Sci (2021) Cilt : 11 Sayı : 1 Sayfa : 74-80
Beta-Sitosterol and its Antinociceptive Mechanism Action
A. A. Şakul & M. E. Okur. Beta-Sitosterol and its Antinociceptive Mechanism Action
Ankara Universitesi Eczacilik Fakultesi Dergisi (2021) Cilt : 45 Sayı : 1 Sayfa : 238-252
Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in Mice
M. Y. Günal, A. A. Şakul, A. B. Çağlayan, F. Erten, Ö. E. Durmaz Kurşun, E. Kılıç & K. Şahin. Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in Mice. Neurotox Res (2021) Cilt : 39 Sayı : 5 Sayfa : 1543-1550
Squalene Attenuates the Oxidative Stress and Activates AKT/mTOR Pathway Against Cisplatin-Induced Kidney Damage in Mice
A. A. Şakul, M. Ozansoy, B. Elibol, Ş. Ayla, M. Y. Günal, Y. Yozgat Byrne, S. H. Başağa, K. ŞAHİN, R. Kazancıoğlu & Ü. Kılıç. Squalene Attenuates the Oxidative Stress and Activates AKT/mTOR Pathway Against Cisplatin-Induced Kidney Damage in Mice. Turk J Biol (2019) Cilt : 43 Sayı : 3 Sayfa : 179-188
A Pyridoindole Antioxidant SMe1EC2 Regulates Contractility, Relaxation Ability, Cation Channel Activity, and Protein-Carbonyl Modifications in the Aorta of Young and Old Rats with or Without Diabetes Mellitus
A. A. Şakul, N. Arı, R. Sotnikova, F. G. Ozansoy & Ç. Karasu. A Pyridoindole Antioxidant SMe1EC2 Regulates Contractility, Relaxation Ability, Cation Channel Activity, and Protein-Carbonyl Modifications in the Aorta of Young and Old Rats with or Without Diabetes Mellitus. Geroscience (2018) Cilt : 40 Sayı : 4 Sayfa : 377-392
Age- and Diabetes-Induced Regulation of Oxidative Protein Modification in Rat Brain and Peripheral Tissues: Consequences of Treatment with Antioxidant Pyridoindole
A. A. Şakul, A. Cumaoğlu, E. Aydın, N. Arı, N. Dilsiz & Ç. Karasu. Age- and Diabetes-Induced Regulation of Oxidative Protein Modification in Rat Brain and Peripheral Tissues: Consequences of Treatment with Antioxidant Pyridoindole. Exp Gerontol (2013) Cilt : 48 Sayı : 5 Sayfa : 476-484
Cytpotoxic Effects of Arctium Minus Methanol Extract on Various Cancer Cell Lines
Sayın Şakul Ayşe Arzu, Yozgat Byrne Yasemin, Karadağ Ayşe Esra, Altınalan Ebrar, Çimen Şeyma, Okur Mehmet Evren. Cytpotoxic Effects of Arctium Minus Methanol Extract on Various Cancer Cell Lines. 2022. Özgün Makale. Ankara Ecz. Fak. Derg.